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Journal of the Korean Society for Environmental Analysis 2008;11(2):109-118.
Contamination of Veterinary Antibiotics and Antimicrobials in Han River Basin
한강수계 상류지역의 동물용 항생제 및 합성항균제 잔류실태 파악
김주형1, 박찬구2, 김민영2, 안승구2
1서울시보건환경연구원
2서울시립대학교
Abstract
This study was conducted to investigate the pharmaceutical pollution in the upper Han River which is used as drinking water for the Metropolitan area and on evaluate the its influences to the human health and ecosystem. The target materials were 13 species of animal antibiotics as tetracycline, sulfonamide, quinolone antibiotics and etc. that are considerable in their productivity, drainage to the environment and simplicity for analysis. And the purposed regions were the upper Han River area, and the South and North Han river area. And Samples were collected and analyzed at low, medium and high-water seasons. As results, florfenicol (100%), sulfadimethoxine (88%) and enrofloxacin were the most abundant at medium-water season. At the high-water season, some sulfuric antibiotics and florfenicol were existed as low concentrations but there were no increases in concentration or frequency. Concentration variance during a year is not obvious because seasonal Han river's flow change is not big, though some sulfuric antibiotics increased during dry period. The most abundant material was tetracycline (2,096 ng/L), and the next was oxytetracyclin (1,236 ng/L), and chlortetracyclin (793 ng/L) was the third. And for sulfuric antibiotics, concentration of sulfamethoxazole was the highest as 67 ng/L (avg.), and trimethoprim was also high as 202.3 ng/L (avg).
Key Words: Pharmaceutically active compounds, Municipal sewage, Persistent drug residues, Han River basin, Solid-phase extraction
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